Key result
The ratio of acoustic myography to surface electromyography amplitude significantly differentiated children with muscle disease from normal volunteers (P<0.01), yielding 82% sensitivity and 91% specificity.
Why the study?
Does the ratio of acoustic myography to surface electromyography amplitude accurately diagnose pediatric muscle disease?
Population
27 children aged 7-16 years, comprising 16 with muscle disease and 11 normal volunteers
Comparison
Measurement of acoustic myography to surface… vs Normal volunteers
Design
Case-control
Authors
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AMG/EMG ratio differs in pediatric muscle disease; hypothesis-generating and leaves diagnostic utility open for validation.
Case-Control (n=27)
Does the ratio of acoustic myography to surface electromyography amplitude accurately diagnose pediatric muscle disease?
p-value: p=<0.01
The ratio of acoustic to surface EMG amplitude provides high sensitivity and specificity for diagnosing pediatric muscle disease.
Barry et al. (1990) conducted a case-control in Pediatric muscle disease (n=27). Acoustic myography (AMG) to surface electromyography (EMG) amplitude ratio vs. Normal volunteers was evaluated on AMG to EMG amplitude ratio (p=<0.01). The ratio of acoustic myography to surface electromyography amplitude significantly differentiated children with muscle disease from normal volunteers (P<0.01), yielding 82% sensitivity and 91% specificity.
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