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tiated glycogen-storage disease into a number of different types, and has revealed that the peripheral part of the glycogen molecule can undergo metabolic change independently of the central part. What light these new observations will throw on medicine will become clear early in the second century of glycogen. I believe that we can confidently assume that Claude Bernard would have given his interested approval to the many investi- gations into the structure and biosynthesis of glycogen which have taken place during the last twenty-five years of the first century of this substance.
S. C. Truelove (Sat,) studied this question.