April 4, 2008Angewandte Chemie International Edition473 citations

A Chiral Hypervalent Iodine(III) Reagent for Enantioselective Dearomatization of Phenols

TDToshifumi Dohi AMAkinobu Maruyama NTNaoko Takenaga

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Abstract

The hype about iodine(III): A chiral hypervalent iodine(III) reagent (1) is reported to enantioselectively dearomatize phenols in a highly selective manner (see scheme). This result clearly supports existence of the associative pathway in hypervalent iodine(III)-induced phenolic oxidations.

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Dohi et al. (Fri,) studied this question.

synapsesocial.com/papers/6a612da1346eb5614926b974 https://doi.org/https://doi.org/10.1002/anie.200800464

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