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June 26, 2026Infectious MedicineOpen Access

The 2026 Bundibugyo virus disease outbreak in the Democratic Republic of the Congo: Virology, epidemiology, continental response, and research priorities

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Authors

YZYi ZhangChinese Center For Disease Control and PreventionJRJunkai RenChinese Center For Disease Control and PreventionXMXuejun MaCapital Medical University

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Implication

Review synthesizes the virology, epidemiology, response, and research priorities for Bundibugyo virus disease outbreaks.

Key Points

  • To provide a comprehensive synthesis of the virology, epidemiology, and response to Bundibugyo virus disease outbreaks.
  • Review of the 2026 outbreak data in the Democratic Republic of the Congo, including case reporting and genomic analysis.
  • Exploration of international and continental response strategy by WHO and Africa CDC.
  • Assessment of critical research gaps in relation to Bundibugyo virus.
  • 662 confirmed cases and 124 confirmed deaths reported in DRC by June 10, 2026.
  • The Africa CDC developed a response plan with a budget of $517.7 million over six months.
  • Acknowledgment of unique challenges including lack of licensing for vaccines and therapeutic options.

Cite This Study

Zhang et al. (2026) studied this question.

synapsesocial.com/papers/6a612e04a47b29a8623f6a2ehttps://doi.org/10.1016/j.imj.2026.100270
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