Key result
Mitral transcatheter edge-to-edge repair with MitraClip was complicated by the development of systemic inflammatory response syndrome and delirium in an octogenarian patient.
Case Report (n=1)
This case highlights that systemic inflammatory response syndrome can occur as a non-infectious complication following MitraClip placement.
May signal post-MitraClip inflammatory response in elderly HFpEF; leaves open etiology and incidence in broader cohorts.
An octogenarian patient with multiple comorbid conditions, including heart failure with preserved ejection fraction and primary mitral valve regurgitation, presented with shortness of breath. After echocardiographic confirmation of severe mitral valve regurgitation, the patient underwent mitral transcatheter edge-to-edge repair with the placement of 2 MitraClips (Abbott). After the procedure, the patient developed an unexplained fever, leukocytosis, tachycardia, and tachypnea concerning for possible procedural complications. The course was further complicated by the onset of delirium after the initiation of antibiotic therapy. The infectious work-up results were negative, and the patient's condition improved, suggesting a systemic inflammatory response syndrome.
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Mannina et al. (2024) conducted a case report in Heart failure with preserved ejection fraction and primary mitral valve regurgitation (n=1). MitraClip (mitral transcatheter edge-to-edge repair) was evaluated. Mitral transcatheter edge-to-edge repair with MitraClip was complicated by the development of systemic inflammatory response syndrome and delirium in an octogenarian patient.
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