Key result
TMVr with MitraClip linked to PCIS successfully treated with aspirin and colchicine.
Why the study?
Post-cardiac injury syndrome following transcatheter mitral valve repair using the MitraClip system had not been previously reported.
Case Report (n=1)
Post-cardiac injury syndrome can occur after transcatheter mitral valve repair and responds to anti-inflammatory therapy.
BACKGROUND: Post-cardiac injury syndrome (PCIS) is an inflammatory process that may occur after myocardial infarction, cardiac surgery, percutaneous cardiac interventions or chest trauma. To our knowledge, PCIS following transcatheter mitral valve repair (TMVr) using the MitraClip system has not been reported. CASE SUMMARY: A 79-year-old female with chronic heart failure and severe mitral regurgitation received TMVr using the MitraClip system. After the procedure she developed elevated inflammatory markers, pericardial and pleural effusion. Cardiac magnetic resonance provided signs of pericardial and pleural inflammation. After initiating an anti-inflammatory therapy with Aspirin and Colchicine, inflammatory markers decreased markedly, pleural and pericardial effusions were regressive, and the patient showed rapid clinical improvement. DISCUSSION: Post-cardiac injury syndrome may occur after TMVr and should be considered as a differential diagnosis in patients developing chest pain, signs of pericarditis with or without pericardial effusion and elevated inflammatory markers.
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Alachkar et al. (2020) conducted a case report in Chronic heart failure and severe mitral regurgitation (n=1). Transcatheter mitral valve repair (TMVr) using MitraClip system was evaluated on Post-cardiac injury syndrome (PCIS). Transcatheter mitral valve repair using the MitraClip system can lead to post-cardiac injury syndrome, which was successfully treated with Aspirin and Colchicine in this case.
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