Key result
Cardiopulmonary bypass can cause systemic inflammation and major organ dysfunction through the activation of serum proteins, leucocytes, and endothelial cells.
Population
Cardiac surgical patients undergoing cardiopulmonary bypass (CPB)
Design
Review
Authors
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Anti-inflammatory strategies may reduce CPB-related organ dysfunction; leaves open optimal targets and efficacy in prospective trials.
This review outlines the mechanisms of systemic inflammation during cardiopulmonary bypass and highlights the potential of anti-inflammatory strategies to reduce organ dysfunction.
George Asimakopoulos (1999) conducted a review in Systemic inflammation and organ dysfunction. Cardiopulmonary bypass (CPB) was evaluated. Cardiopulmonary bypass can cause systemic inflammation and major organ dysfunction through the activation of serum proteins, leucocytes, and endothelial cells.
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