Key result
Retinal argon laser photocoagulation increased average Po2 across the inner 50% of the retina compared to untreated retina (22 ± 10 mm Hg vs 14 ± 7 mm Hg; P < 0.01) in cats.
Population
Anesthetized cats (n=13)
Comparison
Retinal argon laser photocoagulation vs Untreated retina
Design
Preclinical
Follow-up
At least 4 weeks
Authors
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Does not support changes in clinical photocoagulation; leaves open translation of oxygenation effects to human retinal disease.
Absolute Event Rate: 22% vs 14%
p-value: p=< 0.01
Retinal argon laser photocoagulation chronically increases inner retinal Po2 in lesioned areas in cats.
Budzynski et al. (2008) studied Retinal argon laser photocoagulation (n=13). Retinal argon laser photocoagulation vs. Untreated retina was evaluated on Average Po2 across the inner 50% of the retina (p=< 0.01). Retinal argon laser photocoagulation increased average Po2 across the inner 50% of the retina compared to untreated retina (22 ± 10 mm Hg vs 14 ± 7 mm Hg; P < 0.01) in cats.
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