Lung Transplant Go (LTGO): A Randomized Controlled Trial to Evaluate the Efficacy of a Telerehabilitation Behavioral Exercise Intervention after Lung Transplantation

The Lung Transplant GO (LTGO) randomized controlled trial evaluated the efficacy of a telerehabilitation behavioral exercise program after lung transplantation compared to enhanced usual care (EUC). We hypothesized that the LTGO treatment condition would show significantly greater improvements in change scores from baseline to 3 and 6 months for outcomes of physical function, physical activity, and blood pressure control compared to the EUC condition. The sample included 88 lung transplant recipients (LTRs) randomized 1:1 to either LTGO or EUC. No statistically significant differences in change scores for physical function, physical activity, and blood pressure control were found between treatment groups at 3 and 6 months. While no statistically significant difference in outcomes were found between groups, null findings are not uncommon. These findings and the discussion of post-trial considerations are important for the design of future trials to inform the field of telerehabilitation.