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August 13, 2026Interactive Journal of Medical ResearchOpen Access

Patient-Reported Quality of Life in Lung Transplantation: Prospective Cohort Study

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Authors

PLPeng LiJWJiawei WangHWHongyi Wang

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Overview

Prospective cohort study assesses quality of life changes in lung transplant patients, highlighting key improvements post-surgery.

Key Points

  • This study aimed to evaluate quality of life and its longitudinal changes after lung transplantation using a disease-specific instrument.
  • Single-center prospective cohort study at Xi'an Jiaotong University Lung Transplantation Center.
  • 66 patients screened; quality of life assessed at baseline and serially up to 6 months post-transplant.
  • Random-intercept linear mixed models used to analyze changes across 7 quality of life domains.
  • Significant time effects in 6 of 7 domains (P<.01), with health perceptions showing largest improvement (MD -1.58 at month 6; P<.001).
  • Notable improvements in respiratory symptoms (MD -0.95 at month 6; P<.001) and anxiety/depression (MD -0.82 at month 6; P<.001).
  • Global well-being improved (MD 1.18 at month 6; P=.002), with early improvement observed at month 1 (MD 0.71; P=.23).

Cite This Study

Li et al. (2026) studied this question.

synapsesocial.com/papers/6a7d76aa2b0e0cff3f640246https://doi.org/10.2196/86211
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Quality of life and its association with predictors in lung transplant recipients: a latent profile analysis2024 · 1 citations
  2. 2Improvements in Patient-Reported Functioning after Lung Transplant is Associated with Improved Quality of Life and Survival2024
  3. 3Pulmonary Symptoms and Psychological Distress as Correlates and Mediators of Quality of Life in Lung Transplant Recipients: A Cross-Sectional Study2026
  4. 4Dual Impacts of Lung Transplantation on the Recovery and Comorbidity of Interstitial Lung Diseases: A Longitudinal Assessment of the Benefits and Burden2025
  5. 5Uncharted territories on pediatric heart and lung transplant patients’ health-related quality of life: A scoping review2025 · 3 citations