Catalytic C−H Activation of sp3 C−H Bonds inα-Position to a Nitrogen Atom—Two New Approaches

A very promising approach for the efficient synthesis of complex amines is provided by the transition metal catalyzed activation of sp3 C−H bonds in the position α to a nitrogen atom. Two recent publications show that this approach can be realized impressively by the use of rhodium and iridium catalysts (see scheme; cod=1,5-cyclooctadiene).