Key result
AI research in aortic valve disease grows steadily, focusing on diagnosis, risk stratification, and prognosis.
Why the study?
The knowledge structure of artificial intelligence technology applications in aortic valve disease remained unsystematically characterized.
Systematic Review (n=270)
Scientometric analysis reveals a rapidly growing body of research on AI applications in aortic valve disease, primarily driven by the US and focused on imaging-based diagnosis and risk stratification.
Maps AI research trends in aortic valve disease; leaves open clinical translation pending prospective validation.
Background Aortic valve disease, particularly aortic stenosis, poses a growing global health burden with aging populations. Artificial intelligence technology offers promising tools for diagnosis, risk stratification, and prognosis prediction, yet the knowledge structure of this interdisciplinary field remains unsystematically characterized. Objective This study aims to conduct a scientometric analysis to delineate the research landscape, identify hotspots, and trace evolutionary trends of AI technology applications in aortic valve disease over the past decade. Methods We retrieved relevant literature published between January 2016 and January 2026 from the Web of Science Core Collection and Scopus databases. After screening, 270 eligible articles were included. CiteSpace and VOSviewer were employed to perform visualization analyses of authors, institutions, countries, journals, keywords, and co-citation networks. Results Annual publications increased steadily, with the United States leading in both output and influence. The Mayo Clinic emerged as the most prolific institution. Research hotspots focused on AI-assisted diagnosis, risk stratification, and prognosis prediction for aortic stenosis, primarily using deep learning and machine learning techniques. Keyword clustering revealed themes spanning disease diagnosis, therapeutic technologies, AI-enabled applications, and clinical outcomes. Co-citation analysis highlighted key studies on AI-enhanced electrocardiography and echocardiography for valve disease detection. Conclusions AI technology research in aortic valve disease is advancing rapidly. Based on the keyword clustering and timeline analysis, we propose a conceptual mapping of AI techniques onto clinical phases. Future efforts should prioritize developing multimodal models, facilitating clinical integration, and enhancing patient lifecycle management.
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Hei et al. (2026) conducted a systematic review in Aortic valve disease (n=270). Artificial intelligence technology was evaluated on Publication trends, research hotspots, and evolutionary trends. Artificial intelligence research in aortic valve disease has increased steadily over the past decade, primarily focusing on AI-assisted diagnosis, risk stratification, and prognosis prediction.
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