Key result
A 40-year-old female with regular cannabis use developed a saddle pulmonary embolism and deep vein thrombosis following orthopedic surgery despite standard prophylaxis, suggesting a potential synergistic risk.
Why the study?
This report explores the potential link between cannabis use and thromboembolic events and emphasizes the need for comprehensive perioperative care in patients with such risk factors.
Does regular cannabis use increase the risk of venous thromboembolism in patients undergoing orthopedic surgery?
Case Report (n=1)
No
Does regular cannabis use increase the risk of venous thromboembolism in patients undergoing orthopedic surgery?
Answers are grounded in this paper and cite their sources.
This case highlights that chronic cannabis use may act synergistically with strong perioperative risk factors (immobility, surgery) to potentiate thrombus formation, warranting careful preoperative risk stratification.
This case report describes the management of a 40-year-old female who developed a saddle pulmonary embolism (PE) following open reduction and internal fixation (ORIF) of a distal tibia fracture. The patient had no significant past medical history except for regular cannabis use. Postoperatively, she developed a deep vein thrombosis (DVT) and a saddle PE, which were managed with catheter-directed thrombectomy and anticoagulation therapy. This report explores the potential link between cannabis use and thromboembolic events and emphasizes the need for comprehensive perioperative care in patients with such risk factors.
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Ayad et al. (2025) conducted a case report in Venous thromboembolism (Saddle pulmonary embolism and deep vein thrombosis) (n=1). Cannabis use was evaluated on Development of saddle pulmonary embolism and deep vein thrombosis. A 40-year-old female with regular cannabis use developed a saddle pulmonary embolism and deep vein thrombosis following orthopedic surgery despite standard prophylaxis, suggesting a potential synergistic risk.
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