Cost effectiveness of the NHS breast screening programme: life table model
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Implication
Randomized trial assesses cost effectiveness of breast screening in women, suggesting moderate viability at standard thresholds.
Key Points
- To evaluate the cost effectiveness of the NHS breast screening programme considering benefits, harms, and costs.
- Life table model comparing data from two cohorts of 364,500 women, one with screening and another without screening for 35 years.
- Follow-up included data on breast cancer diagnoses, deaths from breast cancer, and costs of treatment.
- Probabilistic sensitivity analysis analyzed uncertainty in key input parameters.
- Screening led to 1521 fewer deaths from breast cancer but resulted in 2722 overdiagnoses.
- An increase of 6907 person years of survival was observed in the screened cohort with an additional cost of £20,800 per QALY gained.
- Moderate likelihood of being cost-effective at a threshold of £20,000 per QALY gained in 45% of scenarios, with a reduction in QALYs in 12% of scenarios.
Cite This Study
Pharoah et al. (2013) studied this question.