Key result
Chronic chagasic cardiomyopathy involves infection-associated events that compromise microvasculature function and result in hypoperfusion, sharing abnormalities with other congestive cardiomyopathies.
Population
Human and animal models of chronic chagasic cardiomyopathy
Design
Review
Authors
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Microvascular hypoperfusion may drive Chagas cardiomyopathy progression; leaves open targeted therapies pending prospective trials.
Chronic chagasic cardiomyopathy is driven by microvascular dysfunction and hypoperfusion, sharing mechanisms with other chronic congestive cardiomyopathies.
Morris et al. (1990) conducted a review in Chronic chagasic cardiomyopathy. Chagas' disease infection was evaluated. Chronic chagasic cardiomyopathy involves infection-associated events that compromise microvasculature function and result in hypoperfusion, sharing abnormalities with other congestive cardiomyopathies.
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