Key result
Laser lead extraction demonstrated a high clinical procedural success rate of 97.86% and a low overall complication rate of 4.32%, with procedure-related mortality at 0.55%.
Why the study?
The registry was conducted to investigate the safety and efficacy of laser lead extraction procedures in Germany.
Observational (n=2,524)
Yes
Laser lead extraction demonstrates high clinical success (97.86%) and low procedure-related complications (4.32%) in a large national registry.
Supports laser lead extraction in experienced centers; extends real-world registry data but leaves comparative efficacy open.
AIMS: The GermAn Laser Lead Extraction RegistrY: GALLERY is a retrospective, national multicentre registry, investigating the safety and efficacy of laser lead extraction procedures in Germany. METHODS AND RESULTS: Twenty-four German centres that are performing laser lead extraction have participated in the registry. All patients, treated with a laser lead extraction procedure between January 2013 and March 2017, were consecutively enrolled. Safety and efficacy of laser lead extraction were investigated. A total number of 2524 consecutive patients with 6117 leads were included into the registry. 5499 leads with a median lead dwell time of 96 (62-141) months were treated. The mean number of treated leads per patient was 2.18 ± 1.02. The clinical procedural success rate was 97.86% and the complete lead removal was observed in 94.85%. Additional extraction tools were used in 6.65% of cases. The rate of procedural failure was 2.14% with lead age ≥10 years being its only predictor. The overall complication rate was 4.32%, including 2.06% major and 2.26% minor complications. Procedure-related mortality was 0.55%. Female sex and the presence of abandoned leads were predictors for procedure-related complications. The all-cause in-hospital mortality was 3.56% with systemic infection being the strongest predictor, followed by age ≥75 years and chronic kidney disease. CONCLUSION: In the GALLERY, a high success- and low procedure-related complication rates have been demonstrated. In multivariate analysis, female sex and the presence of abandoned leads were predictors for procedure-related complications, while the presence of systemic infection, age ≥75 years, and chronic kidney disease were independent predictors for all-cause mortality.
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Pecha et al. (2022) conducted an observational in Patients requiring laser lead extraction (n=2,524). Laser lead extraction was evaluated on Clinical procedural success. Laser lead extraction demonstrated a high clinical procedural success rate of 97.86% and a low overall complication rate of 4.32%, with procedure-related mortality at 0.55%.
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