Key result
Right-sided transvenous lead extraction is linked to ~5 percentage points lower complete radiological success versus left-sided.
Why the study?
Transvenous lead extraction for right-sided electrodes may differ in patient characteristics and outcomes compared to left-sided extraction due to anatomic differences.
Does right-sided transvenous lead extraction reduce procedural success or increase complications compared to left-sided extraction?
Cohort (n=556)
No
Does right-sided transvenous lead extraction reduce procedural success or increase complications compared to left-sided extraction?
Absolute Event Rate: 88.4% vs 93.8%
p-value: p=0.045
Right-sided lead extraction is a higher-risk procedure with lower radiological success and higher complication rates than left-sided extraction, warranting meticulous preprocedural planning.
May warrant procedural caution in right-sided TLE; leaves open whether specialized techniques improve outcomes in prospective studies.
BACKGROUND AND AIMS: Transvenous lead extraction (TLE) is increasingly performed for malfunction or infection of cardiac implantable electronic devices. Because of anatomic differences, TLE for right-sided (RS) electrodes may differ in outcome. This study aimed to evaluate whether RS TLE differs in patient characteristics and outcomes compared to left-sided TLE. METHODS: We retrospectively analyzed patients who underwent TLE at the University Hospital Zurich from 2013 until 2023 regarding clinical and radiological success and complications. RESULTS: A total of 556 patients underwent 568 TLE from January 2013 until December 2023. Patients with RS TLE procedures (n = 147, 25.9%) were older, more often PM-dependent, had longer lead dwell time, more leads with passive fixation and were more often extracted for infection. RS TLE procedures had a longer procedure duration (130 vs. 108 min, p = 0.002), more often needed a snare-bailout strategy (22% vs. 10%, p = 0.0.45), resulted in lower radiological success rates (88.4% vs. 93.8%, p = 0.045) and more major as well as minor complication rates. CONCLUSION: In our retrospective single-center analysis, RS TLE Procedures were more challenging concerning patient characteristics and resulted in lower TLE success as well as higher complication rates.
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Molitor et al. (2026) conducted a cohort in Cardiac implantable electronic device (CIED) malfunction or infection requiring lead extraction (n=556). Right-sided transvenous lead extraction vs. Left-sided transvenous lead extraction was evaluated on Complete radiological success (p=0.045). Right-sided transvenous lead extraction was associated with lower complete radiological success compared to left-sided extraction (88.4% vs. 93.8%, p=0.045) and higher complication rates.
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