High economy and simple elegance distinguish the synthesis of functionalized cyclohexadienes by dearomatization of benzene derivatives. Modern processes of this type rely on the activation of arenes in transition metal complexes (Os, Cr, Mn), additions after Lewis acid complexation, and dihydroxylations catalyzed by enzymes. Stereoselective methods [see, for example, Eq. (a)] and CC bond forming reactions deserve particular attention.
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Thorsten Bach (1996) studied this question.
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