Key result
Local anesthesia for TAVI significantly reduced hospital stay (WMD -2.48; P<0.00001) and major bleeding (OR 0.59) compared to general anesthesia, but increased acute kidney injury (OR 1.31).
Why the study?
The optimal choice of anesthesia for transcatheter aortic valve implantation remains controversial.
Does local anesthesia improve efficacy and safety outcomes compared to general anesthesia in patients undergoing TAVI?
Meta-Analysis (n=23,480)
Does local anesthesia improve efficacy and safety outcomes compared to general anesthesia in patients undergoing TAVI?
Mean Difference: -2.48 (95% CI -2.8–-2.16)
p-value: p=<0.00001
Local anesthesia for TAVI is associated with shorter hospital stays, reduced procedural times, and less major bleeding compared to general anesthesia, though it may increase the risk of acute kidney injury.
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LA may shorten hospital stay after TAVI; leaves open whether randomized trials confirm safety or outcome benefits.
Wang et al. (2023) conducted a meta-analysis in Transcatheter aortic valve implantation (TAVI) (n=23,480). Local anesthesia vs. General anesthesia was evaluated on Hospital stay (WMD -2.48, 95% CI -2.80, -2.16, p=<0.00001). Local anesthesia for TAVI significantly reduced hospital stay (WMD -2.48; P<0.00001) and major bleeding (OR 0.59) compared to general anesthesia, but increased acute kidney injury (OR 1.31).
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