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July 23, 2026BMC PediatricsOpen Access

Parity differences and inflammatory signatures relative to neonatal nutritional status in a community near the Atlantic Ocean coastline of Lagos, Southwest Nigeria: a cross-sectional study

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Authors

BABamgboye M AfolabiTATitilola M. AfolabiVIVictor Inem

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Overview

Cross-sectional study examines neonatal malnutrition's prevalence and its relation to placental factors in pregnant women.

Key Points

  • This study aimed to determine the prevalence of neonatal malnutrition and explore the impact of placental TNF-alpha and IFN-gamma on maternal and neonatal outcomes.
  • Conducted a cross-sectional study among 254 pregnant women in Lagos, Nigeria.
  • Data on maternal sociodemographics and obstetric history were collected using questionnaires.
  • Neonatal nutritional status was assessed using the Ponderal Index Percentile.
  • Severe neonatal malnutrition prevalence was 4.7%, and moderate malnutrition was 5.9%, with the highest rates among first-time mothers.
  • Placental TNF-alpha levels were significantly higher in first-pregnancy mothers (29.7 ± 7.8 pg/mL) compared to second-pregnancy mothers (12.1 ± 4.2 pg/mL) with severely malnourished neonates.

Cite This Study

Afolabi et al. (2026) studied this question.

synapsesocial.com/papers/6a61aea0faa9903c51169d30https://doi.org/10.1186/s12887-026-07368-3
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