Systematic review assesses endovascular thrombectomy efficacy in acute ischemic stroke due to distal medium vessel occlusion, highlighting risks.
Key Points
This review aims to evaluate the safety and efficacy of endovascular thrombectomy in patients with acute ischemic stroke due to distal medium vessel occlusion.
Systematic search of multiple databases for studies evaluating EVT for DMVO.
Assessment of study bias using NOS for observational and RoB 2 for RCTs.
Random-effects meta-analyses conducted to pool outcomes.
No significant differences in excellent functional outcomes between EVT and BMM (OR: 1.02, 95% CI: 0.86-1.21).
EVT associated with higher odds of mortality (OR: 1.28, 95% CI: 1.07-1.54) and sICH (OR: 1.44, 95% CI: 1.04-1.98).
Subgroup analysis shows EVT favors some patients with M2 occlusions (OR: 1.52, 95% CI: 1.07-2.16).