Randomized trial demonstrates lower prevalence of mosaic chromosomal alterations in older adults with HIV, suggesting a divergent biological mechanism.
Key Points
This research investigates the relationship between mosaic chromosomal alterations and HIV, focusing on their prevalence in older adults.
Participants included older adults with and without HIV.
Prevalence of mosaic chromosomal alterations was assessed and compared between groups.
Mosaic chromosomal alterations were significantly lower in people with HIV compared to those without.
Loss of chromosome Y was particularly suppressed in the HIV-positive group.