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ALTHOUGH most of the interest in glucagon has centered upon its effects on carbohydrate metabolism, there has also been evidence that it may play a direct part in the control of the human appetite. Schulman et al.1 found that glucagon, given three times daily to a group of patients in a mental hospital, caused their food intake to diminish and their weight to decrease, and Stunkard, Van Itallie and Reiss2 demonstrated that glucagon would abolish hunger contractions. Because Mayer3 and other investigators2 have indicated that hunger is suppressed at times when there is a large difference in the concentration of . . .
Penick et al. (Thu,) studied this question.