Treatment of hypertension in chronic kidney disease is supported by current evidence, though gaps remain due to the exclusion of patients with kidney failure from most clinical trials.
This review summarizes the evidence for treating hypertension in chronic kidney disease and highlights the lack of data for patients with kidney failure.
Hypertension is both an important cause and consequence of chronic kidney disease. Evidence from numerous clinical trials has demonstrated the benefit of blood pressure control. However, it remains unclear whether available results could be extrapolated to patients with chronic kidney diseases because most studies on hypertension have excluded patients with kidney failure. In addition, chronic kidney disease encompasses a large group of clinical disorders with heterogeneous natural history and pathogenesis. In this paper, we review current evidence supporting treatment of hypertension in various forms of chronic kidney disease and highlight some of the gaps in the extant literature.
Tedla et al. (2011) conducted a review in Hypertension in Chronic Kidney Disease. Treatment of hypertension was evaluated. Treatment of hypertension in chronic kidney disease is supported by current evidence, though gaps remain due to the exclusion of patients with kidney failure from most clinical trials.
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