Why the study?
CKD is associated with elevated blood pressure, and patients with kidney disease have unique co-existing problems, fluid retention, and treatment resistance compared to hypertensive patients without kidney involvement.
This review summarizes the physiologic relationship between hypertension and chronic kidney disease, current anti-hypertensive therapies, blood pressure measurement techniques, and international consensus guidelines.
Synthesizes hypertension-CKD management guidelines for clinicians; leaves open the need for updated RCTs on emerging therapies.
Chronic kidney disease (CKD) is associated with elevated blood pressure, with both entities worsening over time. Patients with kidney disease are unique in terms of co-existing medical problems, proclivity for fluid retention, and resistance to treatment compared to patients with hypertension that do not have kidney involvement. This review will describe the physiologic relationship between hypertension and kidney disease, and describe the many classes of anti-hypertensive medications that curb both diseases. We will explain the correct way to measure and replicate blood pressure readings for patients and include the latest guidelines to follow from our international consensus experts. We have hope for the future as several new treatments are undergoing trials and awaiting approval.
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Colbert et al. (2025) studied this question.
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