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May 24, 2014Journal of EthnopharmacologyOpen Access

Application of proteomics to determine the mechanism of action of traditional Chinese medicine remedies

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Key result

Proteomics has been widely applied to investigate the mechanisms of action of traditional Chinese medicine remedies across various diseases, including neuronal, cardiovascular, and cancer.

Design

Systematic_review

Authors

YLYuanzhi LaoSimcere Pharmaceutical (China)XWXiaoyu WangHenan Institute of TechnologyNXNaihan XuShenzhen Polytechnic

Discussion

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Overview

Advances TCM mechanism studies in cardiovascular disease; extends proteomic applications while leaving clinical translation open.

Study Design

Type

Systematic Review

Structured PICO

E
Exposure
Proteomics applied to traditional Chinese medicine (TCM) research
O
Outcome
Elucidation of the mechanism of action of TCM on various diseases

Proteomics is a valuable tool for elucidating the mechanisms of action of traditional Chinese medicine across various diseases.

Limitations

  • Further studies are required to determine the protein targets of the active compounds, analyze the mechanism of actions in patients, and compare the clinical effects with western medicine
  • Further studies are required to determine the protein targets of the active compounds, analyze the mechanism of actions in patients, compare the clinical effects with western medicine.

Cite This Study

Lao et al. (2014) conducted a systematic review in Neuronal disease, cancer, cardiovascular disease, diabetes, and immunology-related disease. Traditional Chinese Medicine was evaluated on Mechanisms of action of traditional Chinese medicine remedies. Proteomics has been widely applied to investigate the mechanisms of action of traditional Chinese medicine remedies across various diseases, including neuronal, cardiovascular, and cancer.

synapsesocial.com/papers/6a61cffada6914d0ce89a157https://doi.org/10.1016/j.jep.2014.05.022
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