Key result
Left subclavian artery coverage without revascularization during TEVAR did not significantly increase the risk of stroke (0% vs 12.1%, p=0.37) or spinal cord ischemia (5.5% vs 6%, p=0.58).
Why the study?
Ischemic stroke and spinal cord ischemia are severe complications after TEVAR with high fatality, making it important to define risk factors associated with their occurrence.
Does left subclavian artery coverage without revascularization increase the risk of ischemic stroke and spinal cord ischemia in patients undergoing thoracic endovascular aortic repair?
Cohort (n=51)
No
Does left subclavian artery coverage without revascularization increase the risk of ischemic stroke and spinal cord ischemia in patients undergoing thoracic endovascular aortic repair?
Absolute Event Rate: 0% vs 12.1%
p-value: p=0.37
In this small retrospective cohort, LSA coverage without revascularization during TEVAR did not significantly increase the risk of stroke or spinal cord ischemia compared to leaving the LSA uncovered.
LSA coverage without revascularization was not associated with higher stroke or SCI risk; hypothesis-generating and should not yet change practice.
INTRODUCTION: One of the most severe complications after TEVAR is ischemic stroke and spinal cord ischemia (SCI) resulting in severe disability. These complications can be fatal up to 30% of cases, so it is very important to define risk factors associated with the occurrence of such events. The aim of this study was to define the causes and risk factors associated with the occurrence of neurological complications in patients after TEVAR. MATERIALS AND METHODS: We performed a retrospective analysis of 51 patients undergoing TEVAR in the Department of Vascular Surgery of Military Teaching Hospital in Wroclaw between 2014 and 2017. In 18 patients LSA coverage was managed without revascularization (35.29%), and in 33 patients LSA remained uncovered (64.71%). RESULTS: We did not find any statistically significant difference in the incidence of stroke and spinal cord ischemia in patients with covered and uncovered LSA (stroke p = 0.37, SCI p = 0.58). In the group of patients with covered and uncovered LSA, we did not find any significant differences in the incidence of additional comorbidities such as obesity, ischemic heart disease, hypertension or previous stroke. CONCLUSIONS: There is no difference in stroke and SCI occurrence between patients with covered and uncovered LSA. Although there are many studies analysing the risk of such complications, there is no specific consensus regarding the treatment of LSA coverage. Randomised clinical trials on a large group of patients are still needed.
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Janczak et al. (2019) conducted a cohort in Thoracic aortic aneurysm or acute type B aortic dissection (n=51). Left subclavian artery coverage without revascularization vs. Uncovered left subclavian artery was evaluated on Ischemic stroke (p=0.37). Left subclavian artery coverage without revascularization during TEVAR did not significantly increase the risk of stroke (0% vs 12.1%, p=0.37) or spinal cord ischemia (5.5% vs 6%, p=0.58).
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