Key result
Coexisting hypertension in patients with Type II diabetes mellitus significantly increased the prevalence of left ventricular diastolic dysfunction to 80.4% compared to 54.9% in patients with diabetes alone.
Why the study?
Diabetes mellitus is a global health problem with serious complications, and non-invasive assessment of diastolic filling by Doppler echocardiography provides important information about left ventricular status.
Does the presence of hypertension increase the severity of left ventricular diastolic dysfunction in patients with Type II Diabetes Mellitus?
Observational (n=102)
No
Does the presence of hypertension increase the severity of left ventricular diastolic dysfunction in patients with Type II Diabetes Mellitus?
Absolute Event Rate: 80.4% vs 54.9%
p-value: p=0.046
Coexisting hypertension in patients with Type II diabetes mellitus is associated with an increased severity of left ventricular diastolic dysfunction.
Background: Diabetes Mellitus (DM) is a global health problem due to increased prevalence of obesity and physical inactivity. It is common and a serious disease with chronic complications and constitutes a substantial burden for both patient and health care system. Non-invasive assessment of diastolic filling by Doppler echocardiography provides important information about left ventricular status. Objective: To assessment of left ventricular diastolic dysfunction in patients with or without hypertension of Type II Diabetes Mellitus. Materials and Methods: A prospective observational study was carried out at Department of Cardiology, Sher-E-Bangla Medical College, Barishal, Bangladesh from February 2019 to January 2020. We had studied left ventricular function of 102 randomly selected Diabetes Mellitus patients by echocardiography. These patients were divided into two groups, in one group comprising of 51 patients with Type II Diabetes Mellitus without hypertension (DM) were studied & in another group 51 patients having Type II Diabetes Mellitus with hypertension (DM + HTN) were studied. The diagnosis of Type II DM was done according to the criteria laid down by American Diabetes Association 2012. A detailed clinical history was taken using a structured questionnaire prepared by us for left ventricular function evaluation by echocardiography. Results: Both groups showed male preponderance. Our study showed diastolic dysfunction in 68% of patients. The occurrence of incidence of Grade 3 or 4 left ventricular diastolic dysfunction increases with coexisting diabetes mellitus with hypertension. Aging individuals, male population, duration of diabetes, presence of hypertension were determinants for the occurrence of diastolic dysfunction. There was correlation of diastolic dysfunction with retinopathy as well. Early diagnosis and treatment of diabetic cardiomyopathy may improve systolic and diastolic functions of heart. Conclusion: Diastolic dysfunction seems to be a ....
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Hassan et al. (2022) conducted an observational in Type II Diabetes Mellitus with or without hypertension (n=102). Coexisting hypertension vs. Type II Diabetes Mellitus without hypertension was evaluated on Left ventricular diastolic dysfunction (any grade) (p=0.046). Coexisting hypertension in patients with Type II diabetes mellitus significantly increased the prevalence of left ventricular diastolic dysfunction to 80.4% compared to 54.9% in patients with diabetes alone.
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