What is the clinical evidence from this study?

Study design: Cohort. Population: Mortality (n=1568). Intervention: Heavy current smoking vs. Never smoking. Primary outcome: All-cause mortality (HR 2.30, 95% CI 1.34-4.07, p=0.003).

August 1, 2023Journal of Geriatric CardiologyOpen Access

Current and recent cigarette smoking in relation to cardiovascular and non-cardiovascular mortality in an elderly male Chinese population

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Key result

Heavy current smoking in elderly Chinese men significantly increased the risk of all-cause mortality compared to never smoking, with an adjusted hazard ratio of 2.30.

Why the study?

The study was conducted to investigate the association between current and former smoking and the risk of mortality in elderly Chinese men.

Does cigarette smoking status affect the risk of all-cause, cardiovascular, and non-cardiovascular mortality in elderly Chinese men?

Population

1568 elderly men aged ≥ 60 years in a suburban town of Shanghai

Comparison

Current and former smoking categories vs never smoking

Design

Cohort study

Follow-up

Median 7.9 years

Authors

WWWen‐Yuan‐Yue WangShanghai Institute of Hypertension XYXiaofei YeNaval Medical Research Command CMChao‐Ying MiaoShanghai Jiao Tong University

Discussion

Member takes

Implication

May inform risk stratification in elderly men; leaves open causal effects of cessation timing in prospective studies.

Study Design

Type

Cohort (n=1,568)

Multicenter

Structured PICO

Does cigarette smoking status affect the risk of all-cause, cardiovascular, and non-cardiovascular mortality in elderly Chinese men?

Population

1,568 elderly Chinese men aged 60 years and older were followed for a median of 7.9 years to assess the association between current and former cigarette smoking and mortality.

Exposure

Current smoking (heavy >20 cigarettes/day, light-to-moderate ≤20 cigarettes/day) and former smoking (recent ≤5 years, remote >5 years)

Comparator

Never smoking

Outcome

All-cause, cardiovascular, and non-cardiovascular mortalityhard clinical

Main Result

Hazard Ratio: 2.3 (95% CI 1.34–4.07)

Absolute Event Rate: 22.4% vs 24.9%

p-value: p=0.003

Current heavy smoking and recent smoking cessation (≤5 years) are associated with significantly increased risks of all-cause and non-cardiovascular mortality in elderly Chinese men.

Limitations

Smoking habits were collected only at baseline, not during follow-up.
Lack of information on the duration of cigarette smoking among smokers and the intensity of smoking among former smokers.
No information collected on the reasons for smoking cessation.
Insufficient information on non-fatal cardiovascular events, restricting the analysis to mortality data only.
Relatively small sample size.

Cite This Study

Wang et al. (2023) conducted a cohort in Mortality (n=1,568). Heavy current smoking vs. Never smoking was evaluated on All-cause mortality (HR 2.30, 95% CI 1.34-4.07, p=0.003). Heavy current smoking in elderly Chinese men significantly increased the risk of all-cause mortality compared to never smoking, with an adjusted hazard ratio of 2.30.

synapsesocial.com/papers/6a61e91bb3ffb27a727d9ee5 https://doi.org/10.26599/1671-5411.2023.08.005

View Full Paper

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Current and recent cigarette smoking in relation to cardiovascular and non-cardiovascular mortality in an elderly male Chinese population

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Current and recent cigarette smoking in relation to cardiovascular and non-cardiovascular mortality in an elderly male Chinese population

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Also Consider

Also Consider