Key result
Approved COVID-19 vaccines have been reported to have rare or serious adverse cardiovascular effects, with this review presenting updated information on these effects and underlying mechanisms.
Why the study?
Approved COVID-19 vaccines have been reported to have rare or serious adverse cardiovascular effects, requiring updated information on these effects and their underlying mechanisms.
What are the adverse cardiovascular effects and underlying mechanisms associated with approved COVID-19 vaccines?
Systematic Review
What are the adverse cardiovascular effects and underlying mechanisms associated with approved COVID-19 vaccines?
This systematic review summarizes the rare but serious adverse cardiovascular effects associated with various types of COVID-19 vaccines and their potential mechanisms.
Clinicians should monitor for rare serious CV events post-vaccination; extends the evidence base for risk-benefit assessment in research.
Several vaccines against coronavirus disease 2019 (COVID-19)-caused by the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-have been developed since the COVID-19 pandemic began. Of these, 7 have been approved in the World Health Organization's Emergency Use Listing. However, these vaccines have been reported to have rare or serious adverse cardiovascular effects. This review presents updated information on the adverse cardiovascular effects of the approved COVID-19 vaccines-including inactivated vaccines, protein subunit vaccines, virus-like particles, nucleic acid vaccines, and viral vector vaccines-and the underlying mechanisms.
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Huang et al. (2024) conducted a systematic review in COVID-19. COVID-19 vaccines was evaluated on Adverse cardiovascular effects. Approved COVID-19 vaccines have been reported to have rare or serious adverse cardiovascular effects, with this review presenting updated information on these effects and underlying mechanisms.
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