Key result
Epigenetic signals play a key role in the transcriptional programs underlying HFpEF, offering potential for the development of personalized epigenetic biomarkers and targeted therapies.
Why the study?
Prognosis for patients with HFpEF remains unfavourable without effective treatments, prompting the need to consider the role of epigenetic processing and its diagnostic and therapeutic possibilities.
Design
Review
Authors
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HFpEF prognosis remains unaddressed by current therapies; leaves open the need for dedicated trials in this expanding population.
Epigenetic processing represents a promising avenue for the development of novel diagnostic biomarkers and targeted therapies for HFpEF.
Айтбаев et al. (2023) conducted a review in Heart failure with preserved ejection fraction (HFpEF). Epigenetic signals and drugs was evaluated. Epigenetic signals play a key role in the transcriptional programs underlying HFpEF, offering potential for the development of personalized epigenetic biomarkers and targeted therapies.
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