Key result
The ABCD2 score calculated by enrolling physicians was poorly predictive of stroke at 7 days, with an area under the curve of 0.56 and a low sensitivity of 31.6% for a high-risk score greater than 5.
Why the study?
Does the ABCD2 score accurately predict stroke at 7 and 90 days in adult patients presenting to the emergency department with transient ischemic attack?
Population
2056 adults diagnosed with transient ischemic attack in eight Canadian emergency departments, mean age 68.0…
Design
Cohort
Follow-up
90 days
Authors
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ABCD2 score's poor accuracy warrants caution for TIA risk stratification in the ED; leaves open the need for superior tools in prospective validation.
Cohort (n=2,056)
Yes
Does the ABCD2 score accurately predict stroke at 7 and 90 days in adult patients presenting to the emergency department with transient ischemic attack?
Effect estimate: AUC 0.56 (95% CI 0.47-0.65)
The ABCD2 score is inaccurate at predicting imminent stroke in emergency department patients with TIA, challenging its widespread use and current AHA recommendations.
Perry et al. (2011) conducted a cohort in Transient ischemic attack (n=2,056). ABCD2 score was evaluated on Stroke within 7 days (AUC 0.56, 95% CI 0.47-0.65). The ABCD2 score calculated by enrolling physicians was poorly predictive of stroke at 7 days, with an area under the curve of 0.56 and a low sensitivity of 31.6% for a high-risk score greater than 5.
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