A small volume of an erythrocyte suspension was subjected to the action of a manipulated gas bubble set into stable oscillation at 20 kilohertz. Release of hemoglobin occurred when the oscillation amplitude exceeded a critical threshold. Hydrodynamic stresses resulting from acoustically induced small-scale eddying motion near the bubble may be the mechanism of hemolysis.
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James A. Rooney (1970) studied this question.
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