Key result
Double filtration plasma apheresis significantly shortened median hospitalization duration from 10 to 5 days (P=0.009) in patients with severe hypertriglyceridemia-associated acute pancreatitis.
Why the study?
Does double filtration plasma apheresis reduce hospitalization duration and prevent recurrence in patients with severe hypertriglyceridemia-associated acute pancreatitis?
Population
Patients with severe hypertriglyceridemia-associated acute pancreatitis and outpatient asymptomatic…
Comparison
Double filtration plasma apheresis vs No double filtration plasma apheresis
Design
Case-control
Follow-up
2 years (for outpatient cohort)
Authors
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May shorten hospital stay in STAP with TG >5000 mg/dL; leaves open need for randomized trials.
Case-Control (n=48)
Does double filtration plasma apheresis reduce hospitalization duration and prevent recurrence in patients with severe hypertriglyceridemia-associated acute pancreatitis?
Absolute Event Rate: 5% vs 10%
p-value: p=0.009
Double filtration plasma apheresis significantly shortens hospitalization duration and reduces recurrence in patients with severe hypertriglyceridemia-associated acute pancreatitis, particularly when serum triglycerides exceed 5000 mg/dL.
Chang et al. (2015) conducted a case-control in Severe hypertriglyceridemia-associated acute pancreatitis (STAP) (n=48). Double filtration plasma apheresis (DFPP) vs. Without DFPP was evaluated on Median hospitalization duration (days) (p=0.009). Double filtration plasma apheresis significantly shortened median hospitalization duration from 10 to 5 days (P=0.009) in patients with severe hypertriglyceridemia-associated acute pancreatitis.
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