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We have investigated the focusing and dynamics of non-spherical polymeric particles in microfluidic flows at finite Reynolds number. The rotational diameter, Dmax, of a particle, regardless of its cross-sectional shape, was found to determine the final focused position, except for the case of asymmetric disks. Additionally, elongated particles with larger Dmax exhibited longer residence times in a horizontal orientation than those with smaller Dmax. These findings inform approaches to hydrodynamically control shaped and barcoded particles for multiplexed biochemical assays.
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Hur et al. (2011) studied this question.
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