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June 22, 2021Biomarkers in Medicine

Systemic Immune–Inflammation Index Predicts New-Onset Atrial Fibrillation After St Elevation Myocardial Infarction

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Why the study?

The predictive capacity of the systemic immune-inflammation index for detecting new-onset atrial fibrillation following STEMI had not been established.

Does the systemic immune-inflammation index predict new-onset atrial fibrillation following STEMI?

Population

402 STEMI patients

Comparison

Patients with NOAF development vs those without

Key result

A systemic immune-inflammation index cut-off of 1,228,000 predicted new-onset atrial fibrillation following STEMI with 60% sensitivity and 78.1% specificity.

Authors

ABAli BağcıFAFatih Aksoy

Discussion

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Member takes

Overview

May support SII-guided NOAF risk stratification post-STEMI; extends prior biomarker findings in an RCT population.

Study Design

Type

Observational (n=402)

Structured PICO

Does the systemic immune-inflammation index predict new-onset atrial fibrillation following STEMI?

P
Population
402 patients with ST segment elevation myocardial infarction evaluated for the development of new-onset atrial fibrillation.
E
Exposure
Systemic immune-inflammation index (SII) measurement
O
Outcome
New-onset atrial fibrillation (NOAF)hard clinical

The systemic immune-inflammation index is an independent predictor of new-onset atrial fibrillation after STEMI, performing similarly to hs-CRP and better than NLR or PLR.

Cite This Study

Bağcı et al. (2021) conducted an observational in ST segment elevation myocardial infarction (STEMI) (n=402). Systemic immune-inflammation index (SII) was evaluated on New-onset atrial fibrillation (NOAF). A systemic immune-inflammation index cut-off of 1,228,000 predicted new-onset atrial fibrillation following STEMI with 60% sensitivity and 78.1% specificity.

synapsesocial.com/papers/6a625223f5a6cede3a89dba7https://doi.org/10.2217/bmm-2020-0838
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The use of systemic immune-inflammation index to predict new onset atrial fibrillation in the context of acute coronary syndrome2022 · 11 citations
  2. 2Prognostic value of systemic immune-inflammation index (SII) as a novel marker in patients with atrial fibrillation2024 · 1 citations
  3. 3The association between systemic inflammatory response index and new-onset atrial fibrillation in patients with ST-elevated myocardial infarction treated with percutaneous coronary intervention2022
  4. 4The predictive value of systemic immune-inflammation index for long-term cardiovascular mortality in non-ST segment elevation myocardial infarction2024 · 5 citations
  5. 5Risk Stratification in Acute Coronary Syndromes: The Systemic Immune-Inflammation Index as Prognostic Marker2025 · 10 citations