Why the study?
New-onset atrial fibrillation in STEMI patients following PCI worsens prognosis, and this study aimed to explore its association with the systemic inflammatory response index.
Does the systemic inflammatory response index (SIRI) predict new-onset atrial fibrillation in patients with ST-elevated myocardial infarction treated with percutaneous coronary intervention?
Population
616 STEMI patients treated with PCI
Comparison
New-onset atrial fibrillation vs sinus rhythm
Design
Retrospective observational study
Follow-up
Median of 40-month
Key result
Elevated systemic inflammatory response index independently predicted new-onset atrial fibrillation in STEMI patients treated with PCI (OR 1.782, 95% CI 1.675-1.906, P=0.001).
Authors
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SIRI may aid NOAF risk assessment after STEMI PCI; hypothesis-generating and requires prospective validation before clinical use.
Observational (n=616)
No
Does the systemic inflammatory response index (SIRI) predict new-onset atrial fibrillation in patients with ST-elevated myocardial infarction treated with percutaneous coronary intervention?
Odds Ratio: 1.782 (95% CI 1.675–1.906)
p-value: p=0.001
The systemic inflammatory response index (SIRI) is an independent predictor of new-onset atrial fibrillation in STEMI patients undergoing PCI, which is associated with increased long-term mortality.
Wang et al. (2022) conducted an observational in ST-elevated myocardial infarction (STEMI) treated with percutaneous coronary intervention (PCI) (n=616). Systemic inflammatory response index (SIRI) vs. Lower SIRI was evaluated on New-onset atrial fibrillation (NOAF) during hospitalization (OR 1.782, 95% CI 1.675-1.906, p=0.001). Elevated systemic inflammatory response index independently predicted new-onset atrial fibrillation in STEMI patients treated with PCI (OR 1.782, 95% CI 1.675-1.906, P=0.001).