Key result
Transcatheter ASD closure improves LA function and resolves RA and RV functional abnormalities.
Why the study?
Timely intervention in atrial septal defect prevents long-term complications and improves quality of life, but the structural and functional changes in atrial and biventricular dimensions pre- and post-device closure needed evaluation.
Does transcatheter device closure improve atrial and ventricular dimensions and functions in patients with atrial septal defect?
Cohort
No
Does transcatheter device closure improve atrial and ventricular dimensions and functions in patients with atrial septal defect?
Transcatheter device closure of ASD leads to favorable structural and functional echocardiographic changes in both atria and ventricles up to 6 months post-procedure.
Answers are grounded in this paper and cite their sources.
Both ASD closure methods appear safe and effective in this cohort; leaves open need for randomized long-term comparisons.
Background: Atrial septal defect (ASD) is one of the most common congenital heart diseases, with an incidence of 1.6 per thousand live births. In adults, it is 3rd most common congenital heart disease. Timely intervention in ASD prevents long-term complications such as pulmonary hypertension, atrial arrhythmias, and congestive heart failure, and it also improves the quality of life of the patients. Both the treatment options, namely surgical and percutaneous device closure, are safe and effective, with the percutaneous approach being at an advantage of avoiding the need of sternotomy and cardiopulmonary bypass and having a better edge in preservation of RV systolic and diastolic function. Aims and Objectives: To study changes in right atrial and ventricular dimensions with functions pre and post device closure & to compare the biventricular dimensions with functions pre- and post-op, at 1, 3 and 6 months. Materials and Methods: We performed a single center prospective cohort study in patients undergoing transcatheter device closure of ASD to study the improvement in structural and functional changes in heart with the help of two-dimensional Echocardiography. Result: We found noticeable improvement in left atrial reservoir and contraction function and also resolution of Right Atrium (RA) and Right Ventricle (RV) functional abnormalities, and favorable changes in pulmonary arterial pressure and paradoxical septal motion. Conclusion: These changes can be the forerunner of improvement in overall cardiac function and quality of life for the patient.
No takes yet. Share an insight, caveat, or question.
Mahalle et al. (2026) conducted a cohort in Atrial septal defect (ASD). Transcatheter device closure was evaluated on Changes in right atrial and ventricular dimensions and functions. Transcatheter device closure of ASD improved left atrial reservoir and contraction function, resolved RA and RV functional abnormalities, and favorably changed pulmonary arterial pressure.
Synapse has enriched 10 related papers. Consider them for comparative context: