Key result
Arterial stiffness (baPWV) was significantly associated with fluid overload in non-diabetic CKD patients (β 0.27), while left ventricular function (bPEP/bET) was associated in diabetic CKD (β -0.19).
Population
480 patients with stages 4-5 chronic kidney disease, of which 207 were diabetic and 240 had fluid overload.
Design
Cross-sectional
Authors
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Fluid overload links variably to stiffness and LV dysfunction by diabetes status in stage 4-5 CKD; leaves open causal effects and management trials.
Cross-Sectional (n=480)
No
Effect estimate: β 0.27 (95% CI 0.01-0.54)
p-value: p=0.04
Tsai et al. (2014) conducted a cross-sectional in Chronic Kidney Disease (Stages 4-5) (n=480). Arterial stiffness (baPWV) and left ventricular function (bPEP/bET) was evaluated on Relative hydration status (fluid overload) in non-diabetic CKD (β 0.27, 95% CI 0.01-0.54, p=0.04). Arterial stiffness (baPWV) was significantly associated with fluid overload in non-diabetic CKD patients (β 0.27), while left ventricular function (bPEP/bET) was associated in diabetic CKD (β -0.19).
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