Key result
Mechanical mitral valve replacement in children performed after 1990 had significantly lower operative mortality compared to before 1990 (3.6% vs 31%, P=0.02).
Cohort (n=44)
No
Absolute Event Rate: 3.6% vs 31%
p-value: p=0.02
Mechanical mitral valve replacement in children carries a low operative risk in the modern era, with substantially improved late survival irrespective of age and disease aetiology.
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Supports safer contemporary pediatric mechanical MVR; leaves open prospective data on valve durability and reintervention.
Christos Alexiou (2001) conducted a cohort in Mitral valve disease requiring replacement (n=44). Mechanical mitral valve replacement after 1990 vs. Mechanical mitral valve replacement before 1990 was evaluated on Operative mortality (p=0.02). Mechanical mitral valve replacement in children performed after 1990 had significantly lower operative mortality compared to before 1990 (3.6% vs 31%, P=0.02).
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