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Despite a record number of solid organs transplanted in 2023, ongoing issues with donor shortages leave thousands of people in the United States waiting. Increased utilization of donors after circulatory death (DCD) has been the primary driver of the increase in total transplants. Availability of newer technologies including normothermic machine perfusion (NMP), normothermic regional perfusion (NRP), and hypothermic machine perfusion (HMP) have been shown to attenuate ischemia-reperfusion injury and allow for graft viability assessment prior to implantation. Outcomes across all solid organs, especially in higher risk donors, have improved using machine perfusion to decrease rates of primary non-function and damage related to ischemia-reperfusion injury (IRI). Here, we present an overview of deceased donation practices across all solid organs.
Chen et al. (Wed,) studied this question.