Key result
Apolipoprotein B is present in the apical portion of nonabsorptive intestinal epithelial cells and its synthesis increases during active lipid absorption in rats.
Population
Isolated intestinal cells prepared from rats either during active lipid absorption or after biliary diversion
Comparison
Indirect immunofluorescence techniques using an… vs Biliary diversion versus active lipid absorption…
Design
Preclinical
Authors
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Intestinal apoB localization in rats may inform lipid transport; leaves open translation to human malabsorption.
This study demonstrates the presence of apolipoprotein B within intestinal epithelium, providing evidence for its participation in intestinal lipid transport.
Glickman et al. (1976) studied this question. Active lipid absorption vs. Biliary diversion was evaluated on Distribution of apolipoprotein B within intestinal epithelial cells. Apolipoprotein B is present in the apical portion of nonabsorptive intestinal epithelial cells and its synthesis increases during active lipid absorption in rats.
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