Key result
Patients with Becker muscular dystrophy had a high prevalence of subclinical cardiomyopathy, with 74% showing ECG abnormalities and 63% having subnormal systolic function.
Why the study?
What is the prevalence and spectrum of subclinical cardiomyopathy in patients with Becker muscular dystrophy?
Population
19 patients with Becker muscular dystrophy and 22 healthy controls
Design
Cross-sectional
Authors
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Subclinical cardiac involvement is common despite few symptoms in Becker MD; leaves open optimal screening strategies in this population.
Observational (n=41)
No
What is the prevalence and spectrum of subclinical cardiomyopathy in patients with Becker muscular dystrophy?
A high percentage of patients with Becker muscular dystrophy have subclinical cardiomyopathy characterized by left ventricular dilation and global hypokinesia, regardless of age, warranting routine echocardiographic screening.
Steare et al. (1992) conducted an observational in Becker muscular dystrophy (n=41). Becker muscular dystrophy vs. Healthy controls was evaluated on Cardiac involvement (electrocardiographic and echocardiographic abnormalities). Patients with Becker muscular dystrophy had a high prevalence of subclinical cardiomyopathy, with 74% showing ECG abnormalities and 63% having subnormal systolic function.
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