Key result
Epicardial adipose tissue thickness and volume strongly correlate with obesity, insulin resistance, metabolic syndrome, and atherosclerosis, acting via complex two-directional paracrine signaling.
Why the study?
Epicardial fat is an important predictor of cardiovascular disease risk, but further study of the bidirectional molecular mechanisms between the heart and epicardial adipose tissue is needed to understand its role in cardiac physiology and disease.
Design
Review
Authors
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Should not yet alter clinical risk assessment; extends observational links between epicardial fat and metabolic factors.
Epicardial adipose tissue is an important predictor of cardiovascular disease risk and interacts with the heart via complex bidirectional pathways, highlighting its physiological and metabolic significance.
Учасова et al. (2018) conducted a review in Cardiovascular diseases. Epicardial adipose tissue was evaluated. Epicardial adipose tissue thickness and volume strongly correlate with obesity, insulin resistance, metabolic syndrome, and atherosclerosis, acting via complex two-directional paracrine signaling.
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