Key result
Genomic analysis of cocirculating human enterovirus species C isolates in Madagascar revealed a high frequency of inter- and intra-typic genetic recombination, resulting in complex mosaic genomes.
Population
Human enterovirus species C isolates from Madagascar in 2002
Authors
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High recombination frequency in enterovirus C may warrant enhanced genomic surveillance; leaves open effects on virulence and clinical outcomes.
High frequency of inter- and intra-typic genetic recombination constitutes a widespread mechanism of genetic plasticity in cocirculating Human Enteroviruses Species C.
Bessaud et al. (2011) studied Human enteroviruses species C (n=41). Genomic sequencing and phylogenetic analysis vs. Prototype strains and isolates from other countries was evaluated on Genetic diversity and recombination events. Genomic analysis of cocirculating human enterovirus species C isolates in Madagascar revealed a high frequency of inter- and intra-typic genetic recombination, resulting in complex mosaic genomes.
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