Key result
An increased non-HDL-C to HDL-C ratio was significantly associated with an increased risk of coronary artery disease (OR 1.291; 95% CI 1.039-1.561; P=0.013).
Why the study?
The association between the non-HDL-C to HDL-C ratio and the risk of CAD, as well as its prognostic role in CAD, required evaluation.
Does an increased non-HDL-C/HDL-C ratio predict the risk and progression of CAD in patients undergoing coronary angiography?
Population
930 consecutive patients with chest discomfort who underwent coronary angiography
Comparison
Non-HDL-C to HDL-C ratio levels in patients with CAD vs normal coronary angiography
Design
Observational cohort study
Authors
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May support CAD risk stratification in angiography patients; leaves open prospective validation before clinical use.
Observational (n=930)
Does an increased non-HDL-C/HDL-C ratio predict the risk and progression of CAD in patients undergoing coronary angiography?
Odds Ratio: 1.291 (95% CI 1.039–1.561)
p-value: p=0.013
An increased non-HDL-C/HDL-C ratio is significantly associated with a higher risk of CAD, acute coronary syndrome, multivessel disease, and long-term MACEs in patients undergoing coronary angiography.
You et al. (2020) conducted an observational in Coronary artery disease (n=930). Non-HDL-C to HDL-C ratio was evaluated on Risk of coronary artery disease (CAD) (OR 1.291, 95% CI 1.039-1.561, p=0.013). An increased non-HDL-C to HDL-C ratio was significantly associated with an increased risk of coronary artery disease (OR 1.291; 95% CI 1.039-1.561; P=0.013).
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