Candid candoxin: A 16-residue peptide (CDX) that is derived from candoxin binds with a high affinity to nicotinic acetylcholine receptors (see picture), which are highly expressed on the blood–brain barrier. In vivo biodistribution and the anti-glioblastoma effect indicate the potential of CDX as a ligand to enable brain-targeted drug delivery.
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Zhan et al. (2011) studied this question.
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