Current outcomes of off-pump versus on-pump coronary artery bypass grafting: evidence from randomized controlled trials
Key result
Off-pump coronary artery bypass grafting yields similar early and late survival compared to on-pump surgery, but may reduce stroke rates, renal dysfunction, bleeding, and respiratory complications.
Why the study?
Does off-pump coronary artery bypass surgery improve clinical outcomes compared to on-pump surgery in patients with extensive coronary artery disease?
Population
Patients with extensive coronary artery disease
Comparison
Off-pump coronary artery bypass (OPCAB) surgery vs On-pump coronary artery bypass (ONCAB) surgery
Design
Review
Authors
Discussion
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Member takes
Implication
Comparable survival supports technique selection by expertise; reinforces RCT meta-analyses showing ONCAB-OPCAB equivalence.
Structured PICO
Does off-pump coronary artery bypass surgery improve clinical outcomes compared to on-pump surgery in patients with extensive coronary artery disease?
P
Population
Patients with extensive coronary artery disease
I
Intervention
Off-pump coronary artery bypass (OPCAB) surgery
C
Comparator
On-pump coronary artery bypass (ONCAB) surgery
O
Outcome
Operative mortality, mid- and long-term survival, graft patency, completeness of revascularisation, neurologic and neurophysiologic outcomes, and perioperative complicationshard clinical
Off-pump CABG provides similar survival to on-pump CABG while potentially reducing perioperative complications like stroke and bleeding, especially in high-risk patients.
Cite This Study
Fudulu et al. (2016) conducted a review in extensive coronary artery disease. Off-pump coronary artery bypass grafting (OPCAB) vs. On-pump coronary artery bypass grafting (ONCAB) was evaluated. Off-pump coronary artery bypass grafting yields similar early and late survival compared to on-pump surgery, but may reduce stroke rates, renal dysfunction, bleeding, and respiratory complications.