Key result
During neocortical development in rats, functional somatic and dendritic BK channels are inserted into neuronal membranes, with an especially rapid increment in density occurring around P5-P7.
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Characterizes BK channel maturation in developing rat neocortex in vitro; leaves open in vivo roles and human translation.
Kang et al. (1996) studied this question. Postnatal development vs. Immature neurons (P1) was evaluated on Density and properties of BK channels. During neocortical development in rats, functional somatic and dendritic BK channels are inserted into neuronal membranes, with an especially rapid increment in density occurring around P5-P7.
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