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This review presents an overview of the biology and mechanical theories modeling developmental processes in the cardiovascular system to stimulate further biomechanical engineering research.
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This review highlights the role of mechanical forces in cardiovascular development and presents mechanical theories to model developmental processes.
It long has been known that mechanical forces play a role in the development of the cardiovascular system, but only recently have biomechanical engineers begun to explore this field. This paper reviews some of this work. First, an overview of the relevant biology is discussed. Next, a mechanical theory is presented that can be used to model developmental processes. The theory includes the effects of finite volumetric growth and active contractile forces. Finally, applications of this and other theories to problems of cardiovascular development are discussed, and some future directions are suggested. The intent is to stimulate further interest among engineers in this important area of research.
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Larry A. Taber (2001) conducted a review in Cardiovascular development. This review presents an overview of the biology and mechanical theories modeling developmental processes in the cardiovascular system to stimulate further biomechanical engineering research.
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